Endocrine Abstracts

Background and Objectives: Leukocyte telomere length (LTL) is considered as a marker of cellular aging. Brown adipose tissue in women has been claimed to be associated with long life in women. Neuregulin-4 is a new batokine secreted from brown adipose tissue, and it is thought to play a role in the regulation of glucose, lipid metabolism and energy balance. The aim of the study is to examine LTL and serum Neuregulin-4 levels as well as their relations with disease activity, co...

Primary squamous cell carcinoma of the thyroid gland (PSCCT) is a rare neoplasm of the thyroid with a poor prognosis. We present a 70-year-old male patient who presented with a progressively growing mass on the left side of the neck causing shortness of breath. The patient presented with suspicious poorly-differentiated malignancy as a result of the thyroid fine-needle aspiration cytology performed due to the rapidly growing mass. No other primary tumor focus was detected in t...

Background: The main objective of this study is to establish the rate of malignancy in residual thyroid tissue in patients with DTC, and whether the serum thyroglobulin (Tg) level before complementary thyroidectomy and histopathologic characteristics of the tumor would be able to foresee malignancy in residual tissue.Methods: Our study included 58 patients with DTC that underwent complementary thyroidectomy that results were analyzed retrospectively. Pat...

Background and Objective: Smoking increases the risk of Graves’ orbitopathy (GO) in patients with Graves’ disease (GD). Therefore, smoking cessation should be recommended to all patients with GD. This study aimed to investigate whether smoking cessation recommendations were taken into account in patients with GD and whether there was a difference in terms of smoking cessation between those with and without GO.Methods: Smoking status of the case...

Aim: Non-alcoholic steatohepatitis is one of the most common causes of chronic liver disease and the incidence in the population varies from %10–24. TGF- β –1 is the most important TGF- β isoform responsible for fibrosis and its effect on hepatic fibrosis was demonstrated in-vitro and in chronic viral hepatitis. Besides TGF- β is an immunsuppresive cytokine and it is known that low TGF- β activity can trigger autoimmune diseases and inflammation.<...